Niosh and diacetyl and background report

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Jensen, R. Hidden formaldehyde in e-cigarette aerosols. Orr, M. Electronic cigarettes in the USA: a summary of available toxicology data and suggestions for the future. Pellegrino, R. Electronic cigarettes: an evaluation of exposure to chemicals and fine particulate matter PM. Ann Ig 24 , — Uchiyama, S. Determination of carbonyl compounds generated from the E-cigarette using coupled silica cartridges impregnated with hydroquinone and 2,4-dinitrophenylhydrazine, followed by high-performance liquid chromatography.

Anal Sci 29 , — Williams, M. Allen, J. Clark, S. Hilts, P. Occupational Safety and Health Administration, Draft—Criteria for a recommended standard.

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Occupational Exposure to Diacetyl and 2,3-Pentanedione. National Institute for Occupational Safety and Health Kreiss, K. Clinical bronchiolitis obliterans in workers at a microwave-popcorn plant. Criteria for a recommended standard: occupational exposure to diacetyl and 2,3-pentanedione.

By McKernan, L. Hubbs, A. Necrosis of nasal and airway epithelium in rats inhaling vapors of artificial butter flavoring. Toxicol Appl Pharmacol , — Respiratory and olfactory cytotoxicity of inhaled 2,3-pentanedione in Sprague-Dawley rats. Respiratory toxicologic pathology of inhaled diacetyl in sprague-dawley rats. Morgan, D. Pezzulo, A.

The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia. Larsen, S. Acute airway effects of diacetyl in mice.


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Zaccone, E. Diacetyl and 2,3-pentanedione exposure of human cultured airway epithelial cells: Ion transport effects and metabolism of butter flavoring agents. Popcorn flavoring effects on reactivity of rat airways in vivo and in vitro. Yaghi, A. Harvey, B. Modification of gene expression of the small airway epithelium in response to cigarette smoking.

Patton, J. Inhaling medicines: delivering drugs to the body through the lungs. The direct effect of hyperosmolar agents on ciliary beating of human bronchial epithelial cells.

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Ciliary beating is depressed in nasal cilia from chronic obstructive pulmonary disease subjects. Chilvers, M.

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NIOSH Proposes RELs for Diacetyl and 2,3-Pentanedione -- Occupational Health & Safety

Local mucociliary defence mechanisms. Iida, H. Differential effects of intravenous anesthetics on ciliary motility in cultured rat tracheal epithelial cells. Care Med Leopold, P. Smoking is associated with shortened airway cilia. Satir, P. Overview of structure and function of mammalian cilia. Stannard, W. Ciliary function and the role of cilia in clearance. Workman, A. The effect of drugs and other compounds on the ciliary beat frequency of human respiratory epithelium. Dowling, R. Bacterial toxins which perturb ciliary function and respiratory epithelium. Salathe, M. Regulation of mammalian ciliary beating.

Braiman, A. Efficient mucociliary transport relies on efficient regulation of ciliary beating. Puchelle, E. Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary disease. Thomas, B. Ciliary dysfunction and ultrastructural abnormalities are features of severe asthma.

Ciliary defects in healthy subjects, bronchiectasis, and primary ciliary dyskinesia. Rutland, J. Random ciliary orientation.

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A cause of respiratory tract disease. Karp, P. An in vitro model of differentiated human airway epithelia.

Methods for establishing primary cultures. Airway epithelial toxicity of the flavoring agent, 2,3-pentanedione abstract.

Commonly used food flavouring causing lung disease ​

Toxicologists , Karantza, V. Keratins in health and cancer: more than mere epithelial cell markers. Moll, R. The human keratins: biology and pathology. Jorissen, M. Correlations among mucociliary transport, ciliary function, and ciliary structure.